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Study for molecular evolution using genomic sequence and gene expression profile
We study the molecular basis and evolutionary history for the acquisition of novel feature based on comparative genomics and gene expression profiles using prokaryotes, virus, and animals. Recently we are focusing more on (1) Analysis of data obtained from Next-generation sequencer and development of analysis algorithms, and (2) Dynamics of gene expression profile underlying the evolution of central nervous system and sensory organs. Currently ongoing studies are as follows:
- Dynamic evolution of translation initiation mechanisms
- Genome-wide sequencing of gene expression in trophoblast cell during placental development
- Gene expression profiling of sea urchin larva by next-generation tag sequencing
- Search for the evolutionary origin of protozoan lens-eye
- Evolutionary acquisition of the mechanosensory organ developmental system
- Search for the evolutionary origin of gap junction
- Evolution of animal eye - A case study on eyes of jellyfishes
- Construction of bio-platform for the cell innovation project
